Re: Is number of chiasmata an etiological factor of male infertility?

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Is number of chiasmata an etiological factor of male infertility?

Azoospermia and/or severe oligozoospermia can be treated as principal factors of male infertility. Specifically, azoospermia that stands for 1% of males and 10% of infertile male population has been mostly unexplained (idiopathic), however, it is suspected for its genetic and/or molecular background.1 Pertaining to molecular background of severe oligo-astheno-teratozoospermia (OAT) – the meioti...

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Re: Is number of chiasmata an etiological factor of male infertility?

We would like to thank Kurpisz and Olszewska1 for their commentary on our article2 and we welcome the opportunity to discuss some of the issues addressed by our colleagues. Meiotic studies are considered to have diagnostic value in cases of infertility of unknown aetiology.3 We would like to remark that its application in the context of our article has been done in compliance with the existing ...

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Management of male-factor infertility.

For many years, the management of male-factor infertility has been empirical rather than evidence-based. In current clinical practice, assisted reproductive techniques are the most successful methods of alleviating male-factor infertility. To date, it remains unclear what adjuvant actions can be taken to improve the outcome of assisted reproductive techniques for male-factor infertility. Eviden...

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15 صفحه اول

I-6: Azoospermia Factor in Male Infertility

Background The human Y chromosome is essential for human sex determination and male germ cell development and maintenance. In 1996, Vogt et al. identified three recurrently deleted regions in Yq11 termed the azoospermia factor (AZF). The AZF region is subdivided into three non-overlapping sub-regions called AZFa, AZFb and AZFc and microdeletion in these regions is the most important etiology of...

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ژورنال

عنوان ژورنال: Asian Journal of Andrology

سال: 2014

ISSN: 1008-682X

DOI: 10.4103/1008-682x.137681